Dressing with Topical Application of Epidermal Growth Factor Gel in the Management of Chronic Wounds: a Prospective Study

Wound healing is a physiological phenomenon that involves a complex series of integrated cellular and biochemical responses. Treatment with growth factors is beginning to gain worldwide importance since is an effective method to promote wound healing. There have been many basic research studies on wound healing using several growth factors including basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF), epidermal growth factor (EGF). In this study we have used a topical formulation containing human recombinant epidermal growth factor in treating various types of cutaneous wounds in 25 patients. Outcome of this study showed that wounds can be treated effectively dressing with epidermal growth factor gel. Which promotes the wound healing process, reduces wound pain and thus improves the patients quality of life.